
Updated: October, 2006


Born: 10.5.1941 Status: Married + 3 Address: 16, Ha’oren St., Jerusalem, Israel 95743



1976 - 1979
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Postdoctoral research, Department of Cellular and Molecular Physiology, Harvard Medical School, Boston, MA. Research: Protein degradation in prokaryotic and eukaryotic cells
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1969 - 1975
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Ph.D., Department of Molecular Biology, The Hebrew University - Hadassah Medical School, Jerusalem, Israel. Thesis: "Modifications in the Structure and Function of β-Lactamase" Supervisor: Prof. N. Citri
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1966 - 1968
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M.Sc. - Department of Molecular Biology, The Hebrew University - Hadassah Medical School, Jerusalem, Israel. Thesis: "Induced Synthesis of β-Lactamase" Supervisor: Prof. N. Citri
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1963 - 1965
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B.Sc. in microbiology and physiology, The Hebrew University, Jerusalem, Israel
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1976
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Boston University, Boston, MA. Course: Television Production
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1972
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School of Education, The Hebrew University, Jerusalem, Israel. Course: Production in Educational Television
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1971
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Israel Center of Science Education, the Hebrew University, Jerusalem, Israel. Course: Production of Film Loops in Science Education |



Educational technologies Distributed learning Science teaching Computer-assisted instruction for students with learning disabilities Teenagers' computer game playing Cell biology Microbiology |



2005 - |
Chair, Department of Natural Sciences, The Open University, Israel |
1981 - present |
Senior lecturer, The Open University, Israel |
1985 - 1986 |
Visiting lecturer in physiology, Department of Cell Biology, Harvard Medical School, Harvard University, Cambridge, MA |
1979 - 1981 |
Lecturer, The Open University, Israel |
1978 - 1979 |
Research Associate, Department of Cell Biology, Harvard Medical School, Harvard University, Cambridge, MA |
1976 - 1978 |
Research Fellow, Department of Cell Biology, Harvard Medical School, Harvard University, Cambridge, MA |
1974 - 1975 |
Instructor, Department of Molecular Biology, The Hebrew University -Hadassah Medical School, Jerusalem, Israel |
1971 |
Instructor, Department of Microbiology, Haile Sellasie I University, Addis-Ababa, Ethiopia |
1970 - 1974 |
Assistant, Department of Molecular Biology, The Hebrew University Hadassah Medical School, Jerusalem, Israel |



2002 - present |
Member, Editorial Board, Journal of Computers in Mathematics and Science Teaching, published by the Association for the Advancement of Computing in Education, Charlottesville, VA |
1999 - present |
Program committee member, Annual World conference on Educational Multimedia and Hypermedia and on Educational Telecommunication, Association for the Advancement of Computing in Education |
1995 - 2001 |
Head, Instructional Software and Multimedia Development Unit, The Open University, Israel |
1988 - 1998 |
Scientific and pedagogic supervisor, Edunetics Educational Systems, Israel / USA |
1987 - 1992 |
Member, Microbiology and Molecular Biology Subcommittee, the Academy of the Hebrew Language, Israel |



1. |
Association for the Advancement of Computing in Education |
2. |
Israel Association for Computers and Education |
3. |
Israel Society of Microbiology |
4. |
Israel Society of Biochemistry |



Personal awards
The Sulka award for distinguished M.Sc. thesis, The Hebrew University Hadassah Medical School, Jerusalem, Israel |
Awards for team projects
Plano ISD Curriculum Integration Project, American Association of School Administrators (AASA) Leadership for Learning Award |
Frontier Ahead, An Educational Multimedia CD-ROM, EDDIE ComputEd Learning Lab Education Review Award |



1. |
Klemes, J. and Citri, N. Preparation and Properties of an Immobilized Derivative of Penicillinase, Biotechnol. Bioengineer., 11 (1979), 897-905. |
2. |
Klemes, J. and Citri, N. Catalytic and Conformational Properties of Cross Linked Derivatives of Penicillinase, Biochem. Biophys. Acta, 567 (1979), 401-409. |
3. |
Klemes, J. and Citri, N. Cross-Linking Preserves Conformational Changes Induced in Penicillinase by its Substrates, Biochem. J., 187 (1980), 529-532. |
4. |
Klemes, J., Etlinger, J. D. and Goldberg, A. L. Properties of Abnormal Proteins Degraded Rapidly in Reticulocytes: Intracellular Aggregation of the Globin Molecules Prior to Hydrolysis, J. Biol. Chem., 256 (1981), 8436-8444. |
5. |
Kidron, M., Fibach, E., Klemes, J. and Mayer, M. Changes in Acid Proteolytic Activity During Differentiation of Murine Erythroleukemic Cells, Cell Differentiation, 10 (1981), 309-315. |
6. |
Kidron, M., Freidsman, D. B., Mayer M., Klemes, J. and Fibach, E. Changes in Proteolytic Activities of Human Leukemic Promyelocytes (HL-60 cells) During Maturation, Hoppe-Seyler's Z. Physiol. Chem., 363 (1982), 865-869. |
7. |
Klemes, J., Kidron, M., Mayer, M. and Fibach, E. Inhibition of Phorbol-Ester-Induced Adhesion of Differentiating Human Myeloid Leukemic Cells by Pentamidine-Isethionate, Differentiation, 27 (1984), 141-145. |
8. |
Klemes, J., Godinger, D. and Aronovitch, Y. Hydrogen Peroxide Increases Intracellular Protein Degradation in E. coli, FEMS Microbiol. Letters, 44 (1987), 277-282. |
9. |
Bejarano, I., Klemes, J., Schoulaker-Schwarz, R. and Engelberg-Kulka, H. Energy-Dependent Degradation of λO protein in Escherichia coli, Bacteriol., 175 (1993) , 7720-7723. |
10. |
Henderson, L., Eshet, Y. and Klemes, J.
Educational Multimedia Implementation in Schools: Producer-Teacher-Student Links, in T. Ottman & I. Tomek, eds., Interactive Multimedia and Hypermedia (pp. 531-536). Association of the Advancement of Computers in Education (1998). |
11. |
Engelberg-Kulka, H., Reches, M., Narasimhan, S., Schoulaker-Schwarz, R., Klemes, J., Eizenman, A. and Glazer, G. RexB of Bacteriophage l is an Anti-Cell Death Gene, Proc. Natl. Acad. Sci. USA, 95 (1998), 15481-15486. |
12. |
Henderson, L., Klemes, J. and Eshet, Y. Just playing a game? Educational simulation software and cognitive outcome, J. of Educational Computing Research, 22(1), (2000), 105-129. |
13. |
Henderson, L., Eshet, Y., and Klemes, J. Under the Microscope: Factors Influencing Student Outcomes in a Computer Integrated Classroom, J. of Computers in Mathematics and Science Teaching, 19(3), (2000), 211-236. |
14. |
Eshet, Y., Klemes, J., Henderson, L. and Jalali, S.
A Model of Successful Technology Integration in School Systems, in T. Ottman & I. Tomek, eds., Interactive Multimedia and Hypermedia (pp. 275-280). Association of the Advancement of Computers in Education (2000). |
15. |
Sharon, A., Loya, S., Epstein, A., Mermelstein, B., Perl, B. and Klemes, J. Virtual Schubert: the Teaching of Music from a Distance, Open Education, 1, (2005), 148-156. |
16. |
Klemes, J., Epstein, A., Zuker, M., Grinberg, N., and Ilovitch, T. An Assistive Computerized Learning Environment for Distance-learning Students with Learning Disabilities, Open Learning, 21, (2006), 19-32. |



1. |
Klemes, J., Bejarano, I., Schoulaker-Schwarz, R. and Engelberg-Kulka, H.
"Energy-Dependent Degradation of λO Protein in Escherichia coli", 1993 Meeting on Molecular Genetics of Bacteria and Phages, Cold Spring Harbor, New York. |
2. |
Schoulaker-Schwarz, R., Klemes, J., Eizenman, A., Glazer, G. and Engelberg-Kulka, H.
"The Bacteriophage λrexB Product Prevents the Degradation of Proteins which are Substrates of the ClpP Protease of Escherichia coli", 1996 EMBO Workshop, Salamanca, Spain. |
3. |
Henderson, L., Eshet, Y. and Klemes, J.
"Educational Multimedia Implementation in Schools: Producer-Teacher-Student Links", ED-MEDIA / ED-TELECOM 98, 1998 World conference on Educational Multimedia and Hypermedia and on Educational Telecommunication, Frieburg, Germany. |
4. |
Eshet, Y., Henderson, L. and Klemes, J.
"Breaking the Mold in Plano", 1999 Association for Educational Communication and Technology (AECT) National Conference, Houston, Texas. |
5. |
Klemes, J.
"Instructional Software and Multimedia in Distance Learning," 16th Conference for Computers in Education, 1999, Tel Aviv (Hebrew). |
6. |
Eshet, Y. and Klemes, J.
"Implementation of Technologies in Educational Systems - How to Break the Barriers", 16th Conference for Computers in Education, 1999, Tel Aviv (Hebrew). |
7. |
Bar-Nir, D. and Klemes, J.
"A Virtual Laboratory in Bacterial Identification", The Annual Meeting of the Israeli Society for Microbiology, 2000, Haifa, Israel (Hebrew). |
8. |
Eshet, Y., Klemes, J., Henderson, L. and Jalali, S.
"The Plano Curriculum Integration Project: A Model of Successful Technology Integration in School Systems", ED-MEDIA / ED-TELECOM 2000, World Conference on Educational Multimedia and Hypermedia and on Educational Telecommunication, Montreal, Canada. |
9. |
Loya, S., Epstein, A., Marmelstein, B. and Klemes, J. "Virtual Schubert - Teaching Music from the Distance", The Annual Meeting of the Israeli Association for Computers and Education, 2001, Tel Aviv (Hebrew). |
10. |
Klemes, J., Ilovitch, T., Epstein, A. and Grinberg, N. "Computer Assisted Learning and Multimedia for Distance-Learning Students with Learning Disabilities", The Annual Meeting of the Israeli Association for Computers and Education, 2001, Tel Aviv (Hebrew). |
11. |
Klemes, J., Epstein, A. and Ilovitch, T.
"Computer-Assisted Instruction and Multimedia for Distance-Learning Students with Learning Disabilities at the Open University of Israel", ED-MEDIA / ED-TELECOM 2002, World Conference on Educational Multimedia and Hypermedia and on Educational Telecommunication, Denver, CO. |
12. |
Henderson, L., Klemes, J. and Eshet, Y.
"Researching Teenagers' Recreational Video/Computer Gameplaying", ED-MEDIA / ED-TELECOM 2002, World Conference on Educational Multimedia and Hypermedia and on Educational Telecommunication, Denver, CO. |
13. |
Bar-Nir, D. and Klemes, J.
"Bacteria in a Virtual World: Combining Technologies in Microbiology Teaching at the Open University", Meital Conference, 2002, Haifa (Hebrew). |
14. |
Loya, S., Sharon, A., Epstein, A., Mermelstein, B., Perl, B. and Klemes, J.
"Virtual Schubert: the Teaching of Music from a Distance", World Conference on Open Learning and Distance Education (ICDE), 2004, Hong Kong. |
15. |
Sharon, A. and Klemes, J.
"New Methods in the Teaching of Academic Music Courses from a Distance", The Inter-University Center for e-Learning (IUCEL), 2005, Beer-Sheba, Israel. |
16. |
Eshet, Y. and Klemes, J.
"What does your child do behind the blinking screen? Digital games among children", 10th Annual Conference of the Israeli Internet Association, February 2006, Tel Aviv. |
17. |
Eshet, Y. and Klemes, J.
"The world is a children's game - social aspects of the digital games culture", Annual Meeting of the Israeli Sociological Society, February 2006, Bar Ilan University. |



1. |
Goldberg, A. L., Kowit, J., Etlinger, J. D., and Klemes, J. Selective Degradation of Abnormal Proteins in Animal and Bacterial Cells, in H. L. Segal and D. J. Doyle, eds., Protein Turnover and Lysosome Function (pp. 171-196). New York: Academic Press (1978). |
2. |
Goldberg, A. L., Klemes, J., Murakami, K., Neff, N. M. and Voellmy, R. W. Studies on the Mechanism and Selectivity of Intracellular Protein Breakdown, in S. Rapoport and T. Schewe, eds., Processing and Turnover of Proteins and Organelles in the Cell (pp. 103-106). Pergamon Press (1979). |



1. |
The Cell: Structure and Function (first edition) 1979, 1980: Protein Synthesis, pp. 1-72; Regulation of Protein Synthesis, pp. 77-159; The Cell Cycle I (with A. Markuze-Haas), pp. 1-44; The Cell Cycle II (with A. Markuze-Haas), pp. 47-117. |
2. |
The World of Bacteria, Unit 1, 1985: Landmarks, pp. 3-45; Structure and Function, pp. 49-126; From Cell to Population, pp. 71-112; Environment and Growth (with B. Kimchi), pp. 1-66; Metabolism and Energy (with A. Adam), pp. 69-150. |
3. |
The World of Bacteria, Unit 11, 1991: Pathogenic Bacteria I (with B. Kimchi), pp. 57-110; Pathogenic Bacteria II (with B. Kimchi), pp. 113-190. |
4. |
The Cell: Structure and Function (revised edition), 1993: The Cell Membrane (with I. Levine), pp. 11-103; Introduction to Bioenergetics, pp. 107-173; Synthesis of ATP, pp. 1-138. |
5. |
The Cell: Structure and Function (revised edition), 1994: Protein Synthesis, pp. 1-93. |
6. |
The Cell: Structure and Function, Unit 7 (revised edition), 1995: Protein Synthesis - Regulation and Control, pp. 1-105. |
7. |
Biology -The Unity and Diversity of Life, 2001 (academic supervision of the Hebrew edition of the book, translated from English). |
Instructional Software and Multimedia
1. |
DNA Sequencing (with M. Souroujon), 1996, Content and instructional advisor. |
2. |
Identification of Bacteria (lab simulation on CD-ROM)(with D. Bar-Nir), 1997, Content and instructional supervisor. |
3. |
Introduction to Psychology: Memory (experimental multimedia CD ROM for students with learning disabilities), 2002, Instructional supervisor. |
Supervision of Course Development
1. |
Cell Structure and Function I |
2. |
Cell Structure and Function II |
3. |
The World of Bacteria |
4. |
General Biology I |
5. |
General Biology II |
6. |
Introduction to Biology |
7. |
Laboratory Experiments in Cell Biology |
8. |
Instructional Technology Methods in Education |



Instructional Software and Multimedia
1. |
Rediscover Science (71 interactive multimedia lessons in life science on CD-ROM), grades 6-9, Edunetics Educational Systems, 1990 (Content editor and curriculum coordinator. |
2. |
Rediscover Science (56 interactive multimedia lessons in life science on CD-ROM), grades 9-12, Edunetics Educational Systems, 1992 (Content editor and curriculum coordinator). |
3. |
Rediscover Science (20 interactive multimedia lessons in life science on CD-ROM) grades 3-5, Edunetics Educational Systems, 1993 (Content editor and curriculum coordinator). |
4. |
Changes in Our World (multimedia database on CD-ROM), grade K, Edunetics Educational Systems, 1994 (Content and instructional supervisor). |
5. |
Animals in their World (multimedia database on CD-ROM), grades 1-2, Edunetics Educational Systems, 1995 (Content and instructional supervisor). |
6. |
Animals in our World (multimedia database on CD-ROM), grades 3-5, Edunetics Educational Systems, 1995 (Content and instructional supervisor). |
7. |
Problems in the Park (multimedia simulation on CD-ROM), grades 1-2, Edunetics Educational Systems, 1997 (Content and instructional supervisor). |
8. |
Frontiers Ahead (multimedia simulation on CD-ROM, with Y. Eshet), grades 4-5, Edunetics Educational Systems, 1997 (Content and instructional supervisor). |
9. |
Build Their Home (multimedia simulation on CD-ROM), Grade K, Edunetics Educational Systems, 1998 (Content and instructional supervisor). |
Teachers' Guides
1. |
Eshet, Y., Levine, T., Meidav, M. and Klemes, J. Rediscover Science, Instructional Resource Guide, grades 6-9, Edunetics Educational Systems (1992). |
2. |
Eshet, Y., Levine, T., Meidav, M. and Klemes, J. Rediscover Science, Instructional Resource Guide, grades 9-12, Edunetics Educational Systems (1994). |
3. |
Eshet, Y., Klemes, J. and Snir, Y. Rediscover Science for Middle Schools, Instructional Resource Guide, Edunetics Educational Systems (1994, Hebrew). |


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